@article{JNI13092,
author = {Fathallah Ismail Islim and Saad Moughal and James Ayre and Aubrey Smith and Paul Maliakal and Nayyar Saleem and Hamed Nejadhamzeeigilani and Tufail Patankar},
title = {Large two-centre UK experience with good long-term stability and safety profile in the flow diversion of carotid-ophthalmic aneurysms},
journal = {Journal of Neurointervention},
volume = {2},
number = {0},
year = {2026},
keywords = {},
abstract = {Background: The advent of flow diverting stents has revolutionised the world of endovascular treatment of intracranial aneurysms. This is in particular with side-wall aneurysms such as carotid ophthalmic aneurysms. Despite the strong efficiency of open surgical clipping, it poses a high risk in this location, particularly relating to the optic apparatus. We aim to demonstrate the efficacy and safety profile of flow diversion in this cohort of patients.Methods: This study was a retrospective analysis of carotid-ophthalmic aneurysms treated with flow diversion at two large centres in the UK. The primary radiological outcomes were quantified on dynamic subtraction angiography (DSA), computed tomography angiography (CTA), or magnetic resonance angiography (MRA) using the modified Raymond-Roy criteria. The outcomes were defined as complete occlusion (modified Raymond-Roy criteria (I) and adequate occlusion (modified Raymond-Roy criteria 1 and modified Raymond-Roy criteria (II) at 6-month and 2-year posttreatment. The primary safety outcome was the rate of device-related adverse events. Secondary safety outcomes included time to discharge and functional outcome [modified Rankin score (mRS)] at 6-month follow-up.Results: One hundred and two patients were treated with a flow diverter during the period January 2015 to December 2021. All patients were treated at an elective basis for incidental aneurysms or recurrence of previously ruptured aneurysms. Six types of flow diverters were used from different producers. One hundred patients underwent follow-up with complete occlusion of 91% and adequate occlusion of 100% with a median radiological follow-up of 2 years. Two patients (1.8%) suffered long-term treatment-related complications (mRS >1). No visual complications or deaths were recorded.Conclusions: Flow diversion demonstrates an efficacious and safe treatment for carotid ophthalmic aneurysms, potentially favouring endovascular treatment to other endovascular means or open surgical clipping.},
issn = {3104-8943}, url = {https://jni.amegroups.org/article/view/13092}
}